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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD2
All Species:
15.76
Human Site:
T1968
Identified Species:
57.78
UniProt:
Q9BYW2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYW2
NP_054878.5
2564
287550
T1968
E
P
K
E
S
N
G
T
K
L
E
E
P
I
N
Chimpanzee
Pan troglodytes
XP_516423
2549
285788
T1953
E
P
K
E
S
N
G
T
K
L
E
E
P
I
N
Rhesus Macaque
Macaca mulatta
XP_001113652
2550
286209
T1954
E
P
K
E
S
N
G
T
K
L
E
E
P
I
N
Dog
Lupus familis
XP_864158
2562
287091
T1966
E
P
K
E
G
N
G
T
K
L
E
E
T
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418510
2354
262767
S1780
Q
D
E
E
E
G
V
S
D
V
E
S
E
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783359
3042
342758
V2218
D
V
E
Q
P
P
S
V
A
V
E
T
D
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2LAE1
1759
193210
Y1185
Q
S
D
S
D
E
E
Y
P
E
L
V
I
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
92
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.7
Protein Similarity:
100
98.9
98
94.6
N.A.
N.A.
N.A.
N.A.
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
100
100
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
15
0
15
0
0
0
15
0
0
0
15
0
15
% D
% Glu:
58
0
29
72
15
15
15
0
0
15
86
58
15
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
15
58
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
58
0
% I
% Lys:
0
0
58
0
0
0
0
0
58
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
58
15
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
58
0
0
0
0
0
0
0
15
43
% N
% Pro:
0
58
0
0
15
15
0
0
15
0
0
0
43
0
0
% P
% Gln:
29
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% R
% Ser:
0
15
0
15
43
0
15
15
0
0
0
15
0
0
15
% S
% Thr:
0
0
0
0
0
0
0
58
0
0
0
15
15
0
0
% T
% Val:
0
15
0
0
0
0
15
15
0
29
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _